Senior Manager, Architecture & Components

Working with Us

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.: careers.bms.com/working-with-us .

The Opportunity

At BMS, we're not just building software - we're building the architectural foundations that will define how a global pharmaceutical organisation harnesses AI through to 2030 and beyond. As a Senior Manager in Software Engineering and Full Stack, you'll be the principal technical force behind a shared, production-grade platform that powers analytics, digital products, and autonomous AI workers across our Product Development & Supply (PDS) organisation.

This is a deeply hands-on, senior individual-contributor role. You won't manage people - you'll set the technical bar through architecture, reference implementations, and engineering excellence. Working within our Analytics & AI Enablement Architecture & Components team, you'll sit alongside UI, UX, AI Engineering, and Architecture specialists in a globally distributed, multidisciplinary environment, helping to shape not just what we build, but how the entire organisation builds it.

What You'll Do

Architect a Multi-Service Platform at Scale

Design and build distributed, multi-service platforms that orchestrate work across autonomous services and agents - with conditional routing, parallel execution, and error recovery

Treat the platform as an internal SaaS/PaaS: shared SDKs, service contracts, and reusable components that solution teams consume rather than rebuild from scratch

Build graph-based orchestration workflows that combine LLM reasoning, business logic, real-time data integration, and enterprise security patterns

Create extensible component libraries and platform patterns that serve multiple business domains simultaneously

Build Production-Grade Backend Systems

Develop production FastAPI (or similar) applications with async I/O patterns for persistence and external services

Implement Server-Sent Events (SSE) and WebSocket protocols for real-time streaming responses

Design APIs and event-driven architectures for orchestration and service-to-service communication

Build robust error handling, graceful degradation, and enterprise security integration (SSO, access control), deploying containerised services via CI/CD

Lead Frontend Architecture & Unified Experience

Build modern web frontends (React) and architect micro-frontend and Module Federation compositions so independently developed modules form one seamless, coherent experience

Develop and steward a shared component library and design system used across the entire platform

Design AI-enhanced UI patterns for streaming responses, conversational interfaces, and analytical visualisation

Make MCP a First-Class Platform Capability

Design, build, and host production MCP servers that expose platform services and tools - ensuring the same underlying capabilities power both the web UI and Claude Desktop with no divergence between the two

Define golden-path patterns, shared MCP servers, and reusable templates so solution teams can ship dual-intent solutions rapidly

Establish MCP hosting, versioning, security, and operational standards for enterprise-grade integration

Integrate and Orchestrate LLMs at Scale

Integrate cloud LLM providers (AWS Bedrock or comparable) into platform services

Design prompt management with versioning, templating, and dynamic compilation

Implement conversation and state persistence (e.g., Redis checkpointing) for multi-turn agentic workflows

Build standardised tool-calling that connects agents and external clients to data sources, with the Model Context Protocol as the primary integration surface

Drive Reusability, Observability & Optimisation

Treat internal developers as customers - deliver golden-path templates, clear contracts, and documentation that accelerate delivery across the organisation

Define versioning, contracts, and backward compatibility standards across the component ecosystem

Build observability, tracing, and monitoring for performance, latency, cost, and quality - and continuously optimise resource and token usage across production workflows

Collaborate and Mentor Across the Organisation

Partner with cloud, AI, data, and UX engineers to integrate full-stack work with infrastructure, agentic capabilities, and interaction design

Align with Enterprise engineering and governance teams on shared standards and controls

Provide technical mentorship on system design, solution patterns, and platform best practices - and contribute to architecture reviews and documentation

What You'll Bring

Education

Bachelor's or Master's degree in Computer Science, Engineering, AI, Data Science, or a related field

Experience - Required

6+ years of software engineering experience with deep full-stack delivery, including production experience building LLM-powered or agentic applications

Strong Python expertise, including async patterns (asyncio, async/await) and Python-based automation

Production experience with async web frameworks (FastAPI or similar), REST, and event-driven and streaming architectures (WebSocket/SSE, queues, streams)

Strong working knowledge of modern web frontends (React) and micro-frontend/Module Federation composition

Demonstrated experience designing distributed, multi-service systems and building an internal platform, SaaS/PaaS, or shared developer platform

Experience with agentic orchestration frameworks (LangGraph preferred; LangChain, CrewAI, Autogen or similar) and cloud LLM providers (AWS Bedrock, Azure OpenAI, Anthropic, or OpenAI)

Strong platform and cloud depth: Docker, Kubernetes/Amazon EKS, infrastructure-as-code (CloudFormation), Git and CI/CD, service mesh, policy-as-code (OPA/Gatekeeper), and production observability (Prometheus, Grafana, Loki) on AWS

Experience owning platform governance, security, and self-service onboarding - IAM/SSO, group-based authorisation, and policy-as-code

Critical Platform & Agentic Systems Experience

Built autonomous, multi-step systems that perform complex analytical tasks well beyond simple chatbots

Designed distributed platforms with service orchestration, conditional logic, and state management

Developed and hosted production MCP servers with demonstrated adoption across capabilities

Delivered dual-intent solutions where the same services power both a web experience and an LLM/desktop client via MCP

Designed shared SDKs and contracts and managed API evolution across many consumers

Prompt engineering at scale - templating, versioning, optimisation - and a strong understanding of agentic design patterns (ReAct, Plan-and-Execute, tool-use agents)

Skills & Competencies

Excellent communication and the ability to set technical direction and influence decisions without direct authority

Strong problem-solving capability in globally distributed, cross-functional teams

Hands-on experience implementing Agentic AI solutions and/or MCP

Relevant cloud certification (e.g., AWS) is a plus

Advantageous Experience

Prior experience in global life sciences, pharma, or supply chain - particularly within Product Development & Supply

Experience in regulated environments (GxP, GDPR, PII) and embedding compliance into platform design from the outset

Experience scaling an internal platform across multiple product and domain teams while managing contract and dependency complexity

Experience working internationally with globally dispersed teams

Why This Role?

This is a rare opportunity to operate as a principal-level technical authority at a company actively investing in AI at enterprise scale. You'll have the freedom to architect from first principles, set standards that propagate across an entire organisation, and build the shared foundations that autonomous AI-powered workflows will run on for years to come.

If you're a full-stack engineer with a platform mindset, a passion for agentic AI, and the technical depth to lead without authority - this is the role built for you.

#LI-Hybrid

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

Supporting People with Disabilities

Candidate Rights

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection .

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com . Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.

R1604337 : Senior Manager, Architecture & Components