Human Resources Business Partner, Director- Rare Disease

US - Illinois - Chicago

JOB ID: R-249035 LOCATION: US - Illinois - Chicago WORK LOCATION TYPE: On Site DATE POSTED: Jul. 08, 2026 CATEGORY: Human Resources SALARY RANGE: 167,444.90USD -226,543.10 USD

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission - to serve patients living with serious illnesses - drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Human Resources Business Partner, Director

What you will do

Let’s do this. Let’s change the world. In this senior leadership role, you will shape and deliver people strategies that drive business performance, organizational effectiveness, and talent outcomes across Amgen’s Rare Disease Business Unit (RDBU).

Reporting directly to the Vice President, Human Resources for Global Markets & Policy and dotted line to the Senior Vice President for Rare Disease, the HR Director works with both the RDBU and Global Markets HR senior teams to drive talent strategy and ongoing transformation of Amgen’s nearly 1,000 person Rare Disease business, with the singular goal of better serving our rare disease patients and customers.

As Amgen’s Rare Disease business continues to rapidly scale, this role offers a unique opportunity to contribute directly and meaningfully to Amgen’s overall success, while also being inspired by witnessing directly the benefits to rare disease patients and their caregivers/families. The mission will be palpable every day.

In a fast-paced environment, the HR Director delivers practical solutions to complex business and talent challenges and helps leaders navigate growth and change.

Key Responsibilities

Strategic HR Business Partnership

Serve as a trusted advisor to the Senior Vice President and his extended cross-functional senior leadership team, aligning people strategies to evolving business priorities and enterprise goals.

Develop and execute HR strategies that strengthen organizational effectiveness, leadership capability, employee engagement, and business performance.

Coach leaders on HR and business issues to accelerate change and improve team effectiveness.

Workforce and Talent Development

Work with senior leaders to assess workforce capabilities, identify talent needs, and build forward-looking workforce and succession strategies.

Lead talent management initiatives including leadership development, succession planning, organizational capability building, engagement, and retention.

Partner with HR Centers of Excellence on compensation, talent planning, culture, diversity and inclusion, and workforce strategies.

Drive the attraction, development, and retention of top talent in partnership with Talent Acquisition and business leaders.

Organizational Transformation and Change Leadership

Lead organizational design efforts with leadership teams to improve agility, scalability, and business effectiveness.

Lead and influence large-scale transformation and change management initiatives across therapeutic areas and commercial functions.

Use data, analytics, and organizational insights to inform decisions, surface trends, and drive continuous improvement.

Employee Engagement and HR Excellence

Foster a high-performing, engaged, and inclusive culture aligned with Amgen’s mission and values.

Ensure alignment with employment laws, HR policies, and business practices while balancing business objectives with a strong employee experience.

Stay current on external talent and organizational trends, bringing practical, innovative thought leadership to the business and HR organization.

Cross-Functional Partnership and HR Leadership

Align HR and business partners to deliver integrated, enterprise-level solutions.

This role will have one direct report and will actively invest in coaching, mentoring, and developing HR talent.

Contribute to the broader HR organization by sharing best practices, thought leadership, and innovative approaches that strengthen HR impact across the enterprise.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Human Resources Business Partner will bring an exceptional blend of business savvy and empathy to ensure that we are making the best talent decisions for both our employees and our stakeholders.

Basic Qualifications:

Doctorate degree and 4+ years of Human Resources experience

OR

Master’s degree and 7+ years of Human Resources experience

OR

Bachelor’s degree and 9+ years of Human Resources experience

Preferred Qualifications:

Experience coaching and influencing leaders to drive organizational effectiveness and change.

Experience in HR site leadership in a complex business environment.

Experience partnering with HR Centers of Excellence on talent planning, leadership development, compensation, and workforce strategy.

Demonstrated ability to translate business priorities into strategic and practical HR solutions.

Strong knowledge of employment laws, HR regulations, and relevant business practices.

Strong business acumen, analytical/problem-solving skills, and project/program management capability.

Excellent communication and interpersonal skills; ability to build credibility and influence at senior levels.

Proven ability to collaborate across HR and business functions and manage competing priorities in a fast-paced environment.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.