Manager, PLM Operations

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

The Manager, PLM Operations, is a high-impact role that balances strategic leadership, operational execution, and people development. This position develops key partnerships across Engineering, Quality, Regulatory, Supply Chain, and Commercial departments to enable excellence throughout the product lifecycle. Success in this role looks like a motivated team with clear ownership and predictable delivery, resulting in high PLM-stakeholder satisfaction. The ideal candidate has strong negotiating and influencing skills, the ability to handle multiple tasks in parallel, and communicate effectively across all levels of the organization.

Responsibilities:

Lead team of Change Analysts supporting New Product Introduction and Sustaining Operations at multiple sites. Align business demand with team capacity.

Set clear performance expectations and champion employee development.

Acts as subject matter expert (SME) of PLM process requirements; define and apply best practices.

Lead global alignment discussions on strategy and requirements.

Trend, analyze, and report on change management data in order to improve product and process; develop recommendations based on data analysis.

Lead initiatives to reduce aging changes, improve throughput, and eliminate recurring process pain points.

Requirements:

Bachelor’s Degree in an engineering or scientific discipline

Typically requires 8+ years of relevant experience in engineering or similar with hands‑on understanding of PLM systems (e.g., Teamcenter or similar) and product lifecycle processes.

Strongly preferred: 1-3 years of management experience

Consistent track record of collaboration, including the ability to work with cross-functional teams across complex ecosystems with an enterprise mindset

Proven people‑management skills, including coaching, performance management, and conflict resolution.

Ability to navigate and influence across all levels of an organization, translating strategic vision into tangible outcomes

Experience applying quality regulation standards (e.g. 21CFR820, ISO 13485, ISO 14971, IVDD)

Strong understanding of manufacturing methods & terminology.

Knowledge of Lean Tools and Root Cause Analysis methodologies.

Proficient in process mapping with demonstrated track-record of driving solutions through continuous improvement culture and project management.

Occasional travel, night and/or weekend work may be required to support 24-hour global manufacturing operation.

The estimated base salary range for the Manager, PLM Operations role based in the United States of America is: $107,700 - $161,500. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role. Most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.